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PLT Data is a graphical interface to create NONMEM* datasets from source files:
Source files can be from Excel (.xls, .xlsx, .csv), SAS (.xpt, .sas7bdat), or text format (pipe-delimited)
Files are converted to csv format, summarized, and a portion displayed in a text file. Link sample / Cp data (options -- only needed if these data are in separate files).
Merge dosing and DV (Cp) data into a format accessible to NONMEM.
Time: calculate 'time after dose'; time in hours or days; referenced to first sample or dose or preceding midnight
Add covariate data (demographics / vital signs / lab values to dataset.
Calculate additional covariates (BMI, BSA, LBM, Elderly (cutoffs of 65, 70, 80 years), GFR (5 equations available).
Graphics: by subject (by period, if in dataset), time-after-dose, composites, dose-normalized
PLT Tools is a suite of tools that facilitates the conduct of NONMEM* analyses and does the following:
Run NONMEM from a graphical interface
Create high-quality graphics
File NONMEM outputs automatically
Perform statistics
Edit Control Streams without leaving PLT Tools
Model diagnostics using xpose†
Summarize runs and prepare a report (RTF format) Create an archive of a project
Select runs to be used by the "Prepare a Report" and Archive Manager tools
PLTconvert is a graphical interface to convert SAS files (SAS7BDAT or XPT) to CSV.
R and R's haven package (both open-source, available at r-project.org), are required.
PLTconvert can manage single files or folders containing multiple files.
Drag-and-drop supported.
* NONMEM is a registered trademark of the Regents of the University of California; NONMEM licenses are obtained from Icon Development Solutions.
† xpose copyright is held by Hooker, Karlsson, Jonsson
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