PLT Tools: Features

additional features
	PLT Tools version 6.0 is available for download for Windows (XP, Vista, 7, 8, or 10) and OS X. The free version provides nearly all features (see licenses to learn about unlocking all features). Many enhancements have been made since the first release in 2008. Additional files created by PLT Tools NONMEM output saved in PDF format for Part 11 compliance (download example). NONMEM output abbreviated using 'nmsee', saved in PDF format (download example). Brief summary of NONMEM output (estimates of THETAS/OMEGAS/SIGMAS, objective function) saved in PDF format (download example). NONMEM output tables reformatted into csv format (download example). Summarize a project Tables summarize population and post hoc parameters and covariates (download example). Tables, graphics, and NONMEM outputs are embedded into a Word document (download example). Specialized outputs for visual predictive check Graphics display observations and (customizable) prediction bands for predictions (download example). Stratification by grouping variables supported. Specialized outputs for likelihood profiles A graphic displays the objective function of each run compared to the run in which the THETA is estimated (download example). Objective function and parameters from all runs aggregated into a spreadsheet (download example). Specialized outputs for bootstrap Objective function and parameters from all runs aggregated into a spreadsheet (download example). Parameters from all runs summarized in a spreadsheet (download example) and displayed in graphics (download example). Specialized outputs for jackknife Graphics display separate fits for data included in the analysis compared to data excluded from the analysis (download example). User-defined graphics scripts A user can write his/her own scripts to create additional graphics or perform statistical analyses: Create a folder USERSCRIPTS in the Project Folder. Within that folder, create a text file 'UserDefinedScript.R'. That file should contain syntactically-correct R commands. The file can contain only the command 'source("SomeOtherFile")'. For initial testing purposes, the user can create a file containing the command 'cat("\n\nHello World\n\n")'. After PLT Tools completes normal execution, it 'source's that file (i.e., reads and executes the contents of the file). If the file is not syntactically correct, error messages appear in the Output window. The user can access most 'objects' created within R. These include: ALL (dataframe): Contents of the AllRecords file. ETAS (dataframe): If a FirstRecords file exists, contents of that file. If FirstRecords does not exist, a subset of ALL (the first record for each ID). DEMO (dataframe): If a covariates file exists, contents of that file. If not, an object created by PLT Tools while processing ALL and ETAS. FILEID (character string): The 13-character timestamp. Many other objects are available. To identify which objects exist, the file UserDefinedScript.R can contain the command 'ls()'; a list of all objects will appear in the output window. The user can access these objects by further editing of the file UserDefinedScript.R. For example, to access the object 'PaperWidth', add the command 'cat("PaperWidth is", PaperWidth, "\n")' to UserDefinedScript.R. If the user wishes to take advantage of certain formatting options used by PLT Tools to create graphics (e.g., to replicate headers and footers that appear in graphics), contact support@PLTsoft.com. xpose Diagnostics PLT Tools files user-created xpose files (e.g., satab, patab, catab, cotab). PLT Tools can create xpose files (e.g., satab, patab, catab, cotab) from AllRecords and FirstRecords tables. Access xpose graphics and tables from a pull-down menu. Access other xpose functions from user-prepared scripts. Email notifications PLT Tools can send email at completion of a run or after NN iterations of a bootstrap.